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Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer

We previously reported MELK (maternal embryonic leucine zipper kinase) as a novel therapeutic target for breast cancer. MELK was also reported to be highly upregulated in multiple types of human cancer. It was implied to play indispensable roles in cancer cell survival and indicated its involvement...

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Detalhes bibliográficos
Main Authors: Chung, Suyoun, Suzuki, Hanae, Miyamoto, Takashi, Takamatsu, Naofumi, Tatsuguchi, Ayako, Ueda, Koji, Kijima, Kyoko, Nakamura, Yusuke, Matsuo, Yo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681500/
https://ncbi.nlm.nih.gov/pubmed/23283305
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