Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.
We have introduced a variety of amino acid substitutions into carboxyl-terminal CA1A2X sequence (C = cysteine; A = aliphatic; X = any amino acid) of the oncogenic [Val12]Ki-Ras4B protein to identify the amino acids that permit Ras processing (isoprenylation, proteolysis, and carboxyl methylation), m...
محفوظ في:
| الحاوية / القاعدة: | Proc Natl Acad Sci U S A |
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| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
National Academy of Sciences
1992
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6403 |
| الوسوم: |
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