Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.

We have introduced a variety of amino acid substitutions into carboxyl-terminal CA1A2X sequence (C = cysteine; A = aliphatic; X = any amino acid) of the oncogenic [Val12]Ki-Ras4B protein to identify the amino acids that permit Ras processing (isoprenylation, proteolysis, and carboxyl methylation), m...

Descripció completa

Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Kato, K, Cox, A D, Hisaka, M M, Graham, S M, Buss, J E, Der, C J
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6403
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!