Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.

We have introduced a variety of amino acid substitutions into carboxyl-terminal CA1A2X sequence (C = cysteine; A = aliphatic; X = any amino acid) of the oncogenic [Val12]Ki-Ras4B protein to identify the amino acids that permit Ras processing (isoprenylation, proteolysis, and carboxyl methylation), m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kato, K, Cox, A D, Hisaka, M M, Graham, S M, Buss, J E, Der, C J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1992
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC49509/
https://ncbi.nlm.nih.gov/pubmed/1631135
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