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Minireview: Genetic basis of heterogeneity and severity in sickle cell disease
Sickle cell disease, a common single gene disorder, has a complex pathophysiology that at its root is initiated by the polymerization of deoxy sickle hemoglobin. Sickle vasoocclusion and hemolytic anemia drive the development of disease complications. In this review, we focus on the genetic modifier...
Uloženo v:
| Vydáno v: | Exp Biol Med (Maywood) |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
SAGE Publications
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4950383/ https://ncbi.nlm.nih.gov/pubmed/26936084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216636726 |
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