Different cAMP sources are critically involved in G protein–coupled receptor CRHR1 signaling

Corticotropin-releasing hormone receptor 1 (CRHR1) activates G protein–dependent and internalization-dependent signaling mechanisms. Here, we report that the cyclic AMP (cAMP) response of CRHR1 in physiologically relevant scenarios engages separate cAMP sources, involving the atypical soluble adenyl...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: Inda, Carolina, dos Santos Claro, Paula A., Bonfiglio, Juan J., Senin, Sergio A., Maccarrone, Giuseppina, Turck, Christoph W., Silberstein, Susana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2016
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949449/
https://ncbi.nlm.nih.gov/pubmed/27402953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201512075
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