B-Raf and CRHR1 Internalization Mediate Biphasic ERK1/2 Activation by CRH in Hippocampal HT22 Cells

CRH is a key regulator of neuroendocrine, autonomic, and behavioral response to stress. CRH-stimulated CRH receptor 1 (CRHR1) activates ERK1/2 depending on intracellular context. In a previous work, we demonstrated that CRH activates ERK1/2 in limbic areas of the mouse brain (hippocampus and basolat...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Bonfiglio, Juan J., Inda, Carolina, Senin, Sergio, Maccarrone, Giuseppina, Refojo, Damián, Giacomini, Damiana, Turck, Christoph W., Holsboer, Florian, Arzt, Eduardo, Silberstein, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416933/
https://ncbi.nlm.nih.gov/pubmed/23371389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1359
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