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cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells

Corticotropin-releasing hormone receptor 1 (CRHR1) activates the atypical soluble adenylyl cyclase (sAC) in addition to transmembrane adenylyl cyclases (tmACs). Both cAMP sources were shown to be required for the phosphorylation of ERK1/2 triggered by activated G protein coupled receptor (GPCR) CRHR...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Inda, Carolina, Bonfiglio, Juan José, dos Santos Claro, Paula A., Senin, Sergio A., Armando, Natalia G., Deussing, Jan M., Silberstein, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434020/
https://ncbi.nlm.nih.gov/pubmed/28512295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02021-7
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