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Different cAMP sources are critically involved in G protein–coupled receptor CRHR1 signaling
Corticotropin-releasing hormone receptor 1 (CRHR1) activates G protein–dependent and internalization-dependent signaling mechanisms. Here, we report that the cyclic AMP (cAMP) response of CRHR1 in physiologically relevant scenarios engages separate cAMP sources, involving the atypical soluble adenyl...
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Publicado no: | J Cell Biol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4949449/ https://ncbi.nlm.nih.gov/pubmed/27402953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201512075 |
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