Context Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow Compartments

Perturbations in CREB binding protein (CREBBP) are associated with hematopoietic malignancies, including myelodysplastic syndrome (MDS). Mice hemizygous for Crebbp develop myelodysplasia with proliferative features, reminiscent of human MDS/myeloproliferative neoplasm-unclassifiable (MDS/MPN-U), and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Zhou, Ting, Perez, Stephanie N., Cheng, Ziming, Kinney, Marsha C., Lemieux, Madeleine E., Scott, Linda M., Rebel, Vivienne I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948888/
https://ncbi.nlm.nih.gov/pubmed/27427906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158649
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