Context Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow Compartments

Perturbations in CREB binding protein (CREBBP) are associated with hematopoietic malignancies, including myelodysplastic syndrome (MDS). Mice hemizygous for Crebbp develop myelodysplasia with proliferative features, reminiscent of human MDS/myeloproliferative neoplasm-unclassifiable (MDS/MPN-U), and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhou, Ting, Perez, Stephanie N., Cheng, Ziming, Kinney, Marsha C., Lemieux, Madeleine E., Scott, Linda M., Rebel, Vivienne I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948888/
https://ncbi.nlm.nih.gov/pubmed/27427906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158649
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