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Enantioselective, Stereodivergent Hydroazidation and Hydroamination of Allenes Catalyzed by Acyclic Diaminocarbene (ADC) Gold(I) Complexes

The gold-catalyzed enantioselective hydroazidation and hydroamination reactions of allenes are presented herein. ADC gold(I) catalysts derived from BINAM were critical for achieving high levels of enantioselectivity in both transformations. The sense of enantioinduction is reversed for the two diffe...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Khrakovsky, Dimitri A., Tao, Chuanzhou, Johnson, Miles W., Thornbury, Richard T., Shevick, Sophia L., Dean Toste, F.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948301/
https://ncbi.nlm.nih.gov/pubmed/27094932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201601550
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