Tyrosine triple mutated AAV2-BDNF gene therapy in a rat model of transient IOP elevation

PURPOSE: We examined the neuroprotective effects of exogenous brain-derived neurotrophic factor (BDNF), which provides protection to retinal ganglion cells (RGCs) in rodents, in a model of transient intraocular pressure (IOP) elevation using a mutant (triple Y-F) self-complementary adeno-associated...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Igarashi, Tsutomu, Miyake, Koichi, Kobayashi, Maika, Kameya, Shuhei, Fujimoto, Chiaki, Nakamoto, Kenji, Takahashi, Hisatomo, Igarashi, Toru, Miyake, Noriko, Iijima, Osamu, Hirai, Yukihiko, Shimada, Takashi, Okada, Takashi, Takahashi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947967/
https://ncbi.nlm.nih.gov/pubmed/27440998
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