A UK feasibility and validation study of the VE1 monoclonal antibody immunohistochemistry stain for BRAF-V600E mutations in metastatic melanoma

BACKGROUND: Determining the BRAF mutation status of patients with advanced metastatic melanoma is essential in order to assess patients' eligibility for targeted BRAF inhibitor therapy. The aim of this study was to validate the utility of immunohistochemistry (IHC) to rapidly obtain the BRAF st...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Lo, Michelle Chin I, Paterson, Anna, Maraka, Jane, Clark, Richard, Goodwill, Joseph, Nobes, Jenny, Garioch, Jennifer, Moncrieff, Marc, Rytina, Ed, Igali, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947692/
https://ncbi.nlm.nih.gov/pubmed/27336602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.106
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