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Utility of BRAF VE1 Immunohistochemistry as a Screening Tool for Colorectal Cancer Harboring BRAF V600E Mutation

BACKGROUND: BRAF mutation has been recognized as an important biomarker of colorectal cancer (CRC) for targeted therapy and prognosis prediction. However, sequencing for every CRC case is not cost-effective. An antibody specific for BRAF V600E mutant protein has been introduced, and we thus examined...

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Detalhes bibliográficos
Publicado no:J Pathol Transl Med
Main Authors: Kwon, Jeong-Hwa, Jeong, Byung-Kwan, Yoon, Yong Sik, Yu, Chang Sik, Kim, Jihun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Pathologists and the Korean Society for Cytopathology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964290/
https://ncbi.nlm.nih.gov/pubmed/29590746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4132/jptm.2018.03.28
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