A UK feasibility and validation study of the VE1 monoclonal antibody immunohistochemistry stain for BRAF-V600E mutations in metastatic melanoma

BACKGROUND: Determining the BRAF mutation status of patients with advanced metastatic melanoma is essential in order to assess patients' eligibility for targeted BRAF inhibitor therapy. The aim of this study was to validate the utility of immunohistochemistry (IHC) to rapidly obtain the BRAF st...

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Bibliografiska uppgifter
I publikationen:Br J Cancer
Huvudupphovsmän: Lo, Michelle Chin I, Paterson, Anna, Maraka, Jane, Clark, Richard, Goodwill, Joseph, Nobes, Jenny, Garioch, Jennifer, Moncrieff, Marc, Rytina, Ed, Igali, Laszlo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Molecular Diagnostics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947692/
https://ncbi.nlm.nih.gov/pubmed/27336602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.106
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