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Immunohistochemistry with Anti-BRAF V600E (VE1) Mouse Monoclonal Antibody is a Sensitive Method for Detection of the BRAF V600E Mutation in Colon Cancer: Evaluation of 120 Cases with and without KRAS Mutation and Literature Review

The major aim of this study was to evaluate the performance of anti-BRAF V600E (VE1) antibody in colorectal tumors with and without KRAS mutation. KRAS and BRAF are two major oncogenic drivers of colorectal cancer (CRC) that have been frequently described as mutually exclusive, thus the BRAF V600E m...

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Библиографические подробности
Опубликовано в: :Pathol Oncol Res
Главные авторы: Dvorak, Katerina, Higgins, Amanda, Palting, John, Cohen, Michael, Brunhoeber, Patrick
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Netherlands 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330560/
https://ncbi.nlm.nih.gov/pubmed/29127628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12253-017-0344-x
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