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Validation of Immunohistochemistry for the Detection of BRAF V600E-Mutated Lung Adenocarcinomas

BRAF V600E mutation, a missense mutation in exon 15 resulting in valine substitution for glutamate at position 600 within the kinase domain of BRAF oncogene, is found in a subset of lung adenocarcinoma (ADC). The usefulness of immunohistochemistry (IHC) as an alternative diagnostic tool has not been...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Gow, Chien-Hung, Hsieh, Min-Shu, Lin, Yen-Ting, Liu, Yi-Nan, Shih, Jin-Yuan
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627826/
https://ncbi.nlm.nih.gov/pubmed/31234388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060866
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