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Intra-tumor heterogeneity of BRAF V600E mutation in lung adenocarcinomas

BRAF mutations exist in numerous types of cancer, including melanomas, colorectal cancers and lung cancers. The V600E-specific inhibitor vemurafenib has marked clinical activity in patients with BRAF V600E-mutated melanoma. However, there are many cases of resistance to vemurafenib. This may be due...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Exp Ther Med
Päätekijät: TATEMATSU, TSUTOMU, SASAKI, HIDEFUMI, SHIMIZU, SHIGEKI, HIKOSAKA, YU, OKUDA, KATSUHIRO, HANEDA, HIROSHI, MORIYAMA, SATORU, YANO, MOTOKI, FUJII, YOSHITAKA
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471699/
https://ncbi.nlm.nih.gov/pubmed/26136882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2298
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