Intra-tumor heterogeneity of BRAF V600E mutation in lung adenocarcinomas

BRAF mutations exist in numerous types of cancer, including melanomas, colorectal cancers and lung cancers. The V600E-specific inhibitor vemurafenib has marked clinical activity in patients with BRAF V600E-mutated melanoma. However, there are many cases of resistance to vemurafenib. This may be due...

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Vydáno v:Exp Ther Med
Hlavní autoři: TATEMATSU, TSUTOMU, SASAKI, HIDEFUMI, SHIMIZU, SHIGEKI, HIKOSAKA, YU, OKUDA, KATSUHIRO, HANEDA, HIROSHI, MORIYAMA, SATORU, YANO, MOTOKI, FUJII, YOSHITAKA
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2015
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471699/
https://ncbi.nlm.nih.gov/pubmed/26136882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2298
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