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Intra-tumor heterogeneity of BRAF V600E mutation in lung adenocarcinomas
BRAF mutations exist in numerous types of cancer, including melanomas, colorectal cancers and lung cancers. The V600E-specific inhibitor vemurafenib has marked clinical activity in patients with BRAF V600E-mutated melanoma. However, there are many cases of resistance to vemurafenib. This may be due...
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| Pubblicato in: | Exp Ther Med |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
D.A. Spandidos
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471699/ https://ncbi.nlm.nih.gov/pubmed/26136882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2298 |
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