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HuR is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells
OBJECTIVE: NOX-1 and NOX-4 are key enzymes responsible for reactive oxygen species (ROS) generation in vascular smooth muscle cells (VSMC). The RNA-binding protein HuR is implicated in post-transcriptional regulation of gene expression; however, its role regulating NOX is unknown. We investigated tr...
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| Publicado no: | J Hypertens |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947528/ https://ncbi.nlm.nih.gov/pubmed/26682942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000000801 |
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