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HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration

BACKGROUND AND PURPOSE: Angiotensin II (AngII) and IL-1β are involved in cardiovascular diseases through the induction of inflammatory pathways. HuR is an adenylate- and uridylate-rich element (ARE)-binding protein involved in the mRNA stabilization of many genes. This study investigated the contrib...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Aguado, A, Rodríguez, C, Martínez-Revelles, S, Avendaño, M S, Zhenyukh, O, Orriols, M, Martínez-González, J, Alonso, M J, Briones, A M, Dixon, D A, Salaices, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459021/
https://ncbi.nlm.nih.gov/pubmed/25653183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13103
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