Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma

PURPOSE: There are no effective treatment options for patients with advanced adenoid cystic carcinoma (ACC). Here, we evaluated the effect of a new small molecule inhibitor of the MDM2-p53 interaction (MI-773) in preclinical models of ACC. EXPERIMENTAL DESIGN: To evaluate the anti-tumor effect of MI...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Clin Cancer Res
Auteurs principaux: Warner, Kristy A., Nör, Felipe, Acasigua, Gerson A., Martins, Manoela D., Zhang, Zhaocheng, McLean, Scott A., Spector, Matthew E., Chepeha, Douglas B., Helman, Joseph, Wick, Michael J., Moskaluk, Christopher A., Castilho, Rogerio M., Pearson, Alexander T., Wang, Shaomeng, Nör, Jacques E.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947417/
https://ncbi.nlm.nih.gov/pubmed/26936915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1698
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires