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Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug

Nitrogen mustard (NM) is a bifunctional alkylating agent that is highly reactive in the skin causing extensive tissue damage and blistering. In the present studies, a modified cutaneous murine patch model was developed to characterize NM-induced injury and to evaluate the efficacy of an indomethacin...

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Detalhes bibliográficos
Publicado no:Exp Mol Pathol
Main Authors: Composto, Gabriella M., Laskin, Jeffrey D., Laskin, Debra L., Gerecke, Donald R., Casillas, Robert P., Heindel, Ned D., Joseph, Laurie B., Heck, Diane E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947376/
https://ncbi.nlm.nih.gov/pubmed/27189522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2016.05.008
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