Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction

Por Jan, Yi-Hua, Heck, Diane E., Casillas, Robert P., Laskin, Debra L., Laskin, Jeffrey D.
Publicado no Chem Res Toxicol (2015)

Cross-Linking of Thioredoxin Reductase by the Sulfur Mustard Analogue Mechlorethamine (Methyl bis(2-chloroethyl) amine) in Human Lung Epithelial Cells and Rat Lung: Selective Inhib...

Por Jan, Yi-Hua, Heck, Diane E., Malaviya, Rama, Casillas, Robert P., Laskin, Debra L., Laskin, Jeffrey D.
Publicado em 2013

Selective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cells

Por Jan, Yi-Hua, Heck, Diane E., Gray, Joshua P., Zheng, Haiyan, Casillas, Robert P., Laskin, Debra L., Laskin, Jeffrey D.
Publicado em 2010

Enantiomeric Composition of the trans-Dihydrodiols Produced from Phenanthrene by Fungi

Por Sutherland, John B., Fu, Peter P., Yang, Shen K., Von Tungeln, Linda S., Casillas, Robert P., Crow, Sidney A., Cerniglia, Carl E.
Publicado em 1993

Sulfur mustard induces an endoplasmic reticulum stress response in the mouse ear vesicant model

Por Chang, Yoke-Chen, Wang, James D., Svoboda, Kathy K., Casillas, Robert P., Laskin, Jeffrey D., Gordon, Marion K., Gerecke, Donald R.
Publicado em 2013

Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide

Por Black, Adrienne T., Hayden, Patrick J., Casillas, Robert P., Heck, Diane E., Gerecke, Donald R., Sinko, Patrick J., Laskin, Debra L., Laskin, Jeffrey D.
Publicado em 2010

Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide

Por Black, Adrienne T., Hayden, Patrick J., Casillas, Robert P., Heck, Diane E., Gerecke, Donald R., Sinko, Patrick J., Laskin, Debra L., Laskin, Jeffrey D.
Publicado em 2011

Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide

Por Black, Adrienne T., Joseph, Laurie B., Casillas, Robert P., Heck, Diane E., Gerecke, Donald R., Sinko, Patrick J., Laskin, Debra L., Laskin, Jeffrey D.
Publicado em 2010

Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug

Por Composto, Gabriella M., Laskin, Jeffrey D., Laskin, Debra L., Gerecke, Donald R., Casillas, Robert P., Heindel, Ned D., Joseph, Laurie B., Heck, Diane E.
Publicado no Exp Mol Pathol (2016)

Histopathological and Molecular Changes in the Rabbit Cornea From Arsenical Vesicant Lewisite Exposure

Por Tewari-Singh, Neera, Goswami, Dinesh G, Kant, Rama, Ammar, David A, Kumar, Dileep, Enzenauer, Robert W, Casillas, Robert P, Croutch, Claire R, Petrash, J Mark, Agarwal, Rajesh
Publicado no Toxicol Sci (2017)

Upregulation of Gamma-2 Laminin-332 in the Mouse Ear Vesicant Wound Model

Por Chang, Yoke-Chen, Sabourin, Carol L. K., Lu, Shou-En, Sasaki, Takako, Svoboda, Kathy K. H., Gordon, Marion K., Riley, David J., Casillas, Robert P., Gerecke, Donald R.
Publicado no J Biochem Mol Toxicol (2009)

Structural Changes in the Skin of Hairless Mice Following Exposure to Sulfur Mustard Correlate with Inflammation and DNA Damage

Por Joseph, Laurie B., Gerecke, Donald R., Heck, Diane E., Black, Adrienne T., Sinko, Patrick J., Cervelli, Jessica A., Casillas, Robert P., Babin, Michael C., Laskin, Debra L., Laskin, Jeffrey D.
Publicado em 2011

Mechanisms Mediating the Vesicant Actions of Sulfur Mustard after Cutaneous Exposure

Por Shakarjian, Michael P., Heck, Diane E., Gray, Joshua P., Sinko, Patrick J., Gordon, Marion K., Casillas, Robert P., Heindel, Ned D., Gerecke, Donald R., Laskin, Debra L., Laskin, Jeffrey D.
Publicado em 2010

Structural Changes in Hair Follicles and Sebaceous Glands of Hairless Mice Following Exposure to Sulfur Mustard

Por Joseph, Laurie B., Heck, Diane E., Cervelli, Jessica A., Composto, Gabriella M., Babin, Michael C., Casillas, Robert P., Sinko, Patrick J., Gerecke, Donald R., Laskin, Debra L., Laskin, Jeffrey D.
Publicado em 2014

Clinical progression of ocular injury following arsenical vesicant lewisite exposure

Por Tewari-Singh, Neera, Croutch, Claire R., Tuttle, Richard, Goswami, Dinesh G., Kant, Rama, Peters, Eric, Culley, Tara, Ammar, David A., Enzenauer, Robert W., Petrash, J. Mark, Casillas, Robert P., Agarwal, Rajesh
Publicado no Cutan Ocul Toxicol (2016)

Mustard vesicants alter expression of the endocannabinoid system in mouse skin

Por Wohlman, Irene M., Composto, Gabriella M., Heck, Diane E., Heindel, Ned D., Lacey, C. Jeffrey, Guillon, Christophe D., Casillas, Robert P., Croutch, Claire R., Gerecke, Donald R., Laskin, Debra L., Joseph, Laurie B., Laskin, Jeffrey D.
Publicado no Toxicol Appl Pharmacol (2016)

Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug

Por Joseph, Laurie B., Composto, Gabriella M., Perez, Roberto M., Kim, Hong-Duck, Casillas, Robert P., Heindel, Ned D., Young, Sherri C., Lacey, Carl J., Saxena, Jaya, Guillon, Christophe D., Croutch, Claire R., Laskin, Jeffrey D., Heck, Diane E.
Publicado no Toxicol Lett (2017)

Therapeutic Potential of a Non-Steroidal Bifunctional Anti-Inflammatory and Anti-Cholinergic Agent against Skin Injury Induced by Sulfur Mustard

Por Chang, Yoke-Chen, Wang, James D., Hahn, Rita A., Gordon, Marion K., Joseph, Laurie B., Heck, Diane E., Heindel, Ned D., Young, Sherri C., Sinko, Patrick J., Casillas, Robert P., Laskin, Jeffrey D., Laskin, Debra L., Gerecke, Donald R.
Publicado no Toxicol Appl Pharmacol (2014)