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Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide

Dermal exposure to the vesicant sulfur mustard causes marked inflammation and tissue damage. Basal keratinocytes appear to be a major target of sulfur mustard. In the present studies, mechanisms mediating skin toxicity were examined using a mouse skin construct model and a full-thickness human skin...

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Detalhes bibliográficos
Main Authors: Black, Adrienne T., Hayden, Patrick J., Casillas, Robert P., Heck, Diane E., Gerecke, Donald R., Sinko, Patrick J., Laskin, Debra L., Laskin, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582383/
https://ncbi.nlm.nih.gov/pubmed/21457723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.03.015
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