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Multi-inhibitor prodrug constructs for simultaneous delivery of anti-inflammatory agents to mustard-induced skin injury

The molecular pathology of a sulfur mustard injury is complex, with at least nine inflammation-related enzymes and receptors upregulated in the zone of the insult. A new approach wherein inhibitors of these targets have been linked by hydrolyzable bonds, either one to one or via separate pre-attachm...

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Bibliografske podrobnosti
izdano v:Ann N Y Acad Sci
Main Authors: Lacey, C. Jeffrey, Wohlman, Irene, Guillon, Christophe, Saxena, Jaya, Fianu-Velgus, Cynthia, Aponte, Erik, Young, Sherri C., Heck, Diane E., Joseph, Laurie B., Laskin, Jeffrey D., Heindel, Ned D.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063683/
https://ncbi.nlm.nih.gov/pubmed/27505078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13177
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