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Multi-inhibitor prodrug constructs for simultaneous delivery of anti-inflammatory agents to mustard-induced skin injury
The molecular pathology of a sulfur mustard injury is complex, with at least nine inflammation-related enzymes and receptors upregulated in the zone of the insult. A new approach wherein inhibitors of these targets have been linked by hydrolyzable bonds, either one to one or via separate pre-attachm...
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| Publicado no: | Ann N Y Acad Sci |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063683/ https://ncbi.nlm.nih.gov/pubmed/27505078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13177 |
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