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Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization
Sperm–egg fusion is the critical step in mammalian fertilization, and requires the interaction between IZUMO1 on the sperm surface and JUNO (also known as folate receptor (FR) 4 or IZUMO1R) on the egg surface. Whereas other FRs bind and uptake folates, JUNO binds IZUMO1 and establishes the cell–cell...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947182/ https://ncbi.nlm.nih.gov/pubmed/27416963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12198 |
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