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Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization

Sperm–egg fusion is the critical step in mammalian fertilization, and requires the interaction between IZUMO1 on the sperm surface and JUNO (also known as folate receptor (FR) 4 or IZUMO1R) on the egg surface. Whereas other FRs bind and uptake folates, JUNO binds IZUMO1 and establishes the cell–cell...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Kato, Kazuki, Satouh, Yuhkoh, Nishimasu, Hiroshi, Kurabayashi, Arisa, Morita, Junko, Fujihara, Yoshitaka, Oji, Asami, Ishitani, Ryuichiro, Ikawa, Masahito, Nureki, Osamu
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947182/
https://ncbi.nlm.nih.gov/pubmed/27416963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12198
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