Carregant...

Autoubiquitination of the Hrd1 ligase triggers protein retrotranslocation in ERAD

Misfolded proteins of the endoplasmic reticulum (ER) are retrotranslocated to the cytosol, where they are polyubiquitinated, extracted from the membrane, and degraded by the proteasome. To investigate how the ER-associated Degradation (ERAD) machinery can accomplish retrotranslocation of a misfolded...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell
Autors principals: Baldridge, Ryan D., Rapoport, Tom A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946995/
https://ncbi.nlm.nih.gov/pubmed/27321670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.048
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!