Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease

Recent work demonstrates that Alport glomerular disease is mediated through a biomechanical strain-sensitive activation of mesangial actin dynamics. This occurs through a Rac1/CDC42 cross-talk mechanism that results in the invasion of the sub-capillary spaces by mesangial filopodia. The filopodia de...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Kidney Int
Autors principals: Dufek, Brianna, Meehan, Daniel, Delimont, Duane, Cheung, Linda, Gratton, Michael Anne, Phillips, Grady, Song, Wenping, Liu, Shiguang, Cosgrove, Dominic
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946972/
https://ncbi.nlm.nih.gov/pubmed/27165837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.02.018
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars