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Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease
Recent work demonstrates that Alport glomerular disease is mediated through a biomechanical strain-sensitive activation of mesangial actin dynamics. This occurs through a Rac1/CDC42 cross-talk mechanism that results in the invasion of the sub-capillary spaces by mesangial filopodia. The filopodia de...
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| 出版年: | Kidney Int |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946972/ https://ncbi.nlm.nih.gov/pubmed/27165837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.02.018 |
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