Role for Macrophage Metalloelastase in Glomerular Basement Membrane Damage Associated with Alport Syndrome

Alport syndrome is a glomerular basement membrane (GBM) disease caused by mutations in type IV collagen genes. A unique irregular thickening and thinning of the GBM characterizes the progressive glomerular pathology. The metabolic imbalances responsible for these GBM irregularities are not known. He...

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Detalhes bibliográficos
Main Authors: Rao, Velidi H., Meehan, Daniel T., Delimont, Duane, Nakajima, Motowo, Wada, Takashi, Ann Gratton, Michael, Cosgrove, Dominic
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698763/
https://ncbi.nlm.nih.gov/pubmed/16816359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050896
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