A carregar...
Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor
Rocaglamide A (RocA) typifies a class of protein synthesis inhibitors that selectively kill aneuploid tumor cells and repress translation of specific mRNAs(1-4). RocA targets eukaryotic initiation factor 4A (eIF4A), an ATP-dependent DEAD-box RNA helicase; its mRNA selectivity is proposed to reflect...
Na minha lista:
| Publicado no: | Nature |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946961/ https://ncbi.nlm.nih.gov/pubmed/27309803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17978 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|