NR2A and NR2B subunits differentially mediate MAP kinase signaling and mitochondrial morphology following excitotoxic insult

NMDA receptors are essential for neurotransmission and key mediators of synaptic signaling, but they can also trigger deleterious degenerative processes that lead to cell death. Growing evidence suggests that selective blockade of the heterogeneous subunits that comprise the NMDA receptor may enable...

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Detalhes bibliográficos
Publicado no:Neurochem Int
Main Authors: Choo, Anthony M., Geddes-Klein, Donna M., Hockenberry, Adam, Scarsella, David, Mesfin, Mahlet N., Singh, Pallab, Patel, Tapan P., Meaney, David F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946952/
https://ncbi.nlm.nih.gov/pubmed/22366650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2012.02.007
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