Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity

BACKGROUND: N-methyl-D-aspartate receptors (NMDARs) are critical for neuronal development and synaptic plasticity. Dysregulation of NMDARs is implicated in neuropsychiatric disorders. Native NMDARs are heteromultimeric protein complexes consisting of NR1 and NR2 subunits. NR2 subunits (NR2A–D) are t...

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Detalhes bibliográficos
Main Authors: Bai, Ning, Hayashi, Hideki, Aida, Tomomi, Namekata, Kazuhiko, Harada, Takayuki, Mishina, Masayoshi, Tanaka, Kohichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652797/
https://ncbi.nlm.nih.gov/pubmed/23641686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-22
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