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Nitric Oxide Suppresses β-Cell Apoptosis by Inhibiting the DNA Damage Response
Nitric oxide, produced in pancreatic β cells in response to proinflammatory cytokines, plays a dual role in the regulation of β-cell fate. While nitric oxide induces cellular damage and impairs β-cell function, it also promotes β-cell survival through activation of protective pathways that promote β...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946431/ https://ncbi.nlm.nih.gov/pubmed/27185882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00262-16 |
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