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Nitric Oxide Suppresses β-Cell Apoptosis by Inhibiting the DNA Damage Response

Nitric oxide, produced in pancreatic β cells in response to proinflammatory cytokines, plays a dual role in the regulation of β-cell fate. While nitric oxide induces cellular damage and impairs β-cell function, it also promotes β-cell survival through activation of protective pathways that promote β...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Oleson, Bryndon J., Broniowska, Katarzyna A., Naatz, Aaron, Hogg, Neil, Tarakanova, Vera L., Corbett, John A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946431/
https://ncbi.nlm.nih.gov/pubmed/27185882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00262-16
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