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How the Location of Superoxide Generation Influences the β-Cell Response to Nitric Oxide
Cytokines impair the function and decrease the viability of insulin-producing β-cells by a pathway that requires the expression of inducible nitric oxide synthase (iNOS) and generation of high levels of nitric oxide. In addition to nitric oxide, excessive formation of reactive oxygen species, such a...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367293/ https://ncbi.nlm.nih.gov/pubmed/25648890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.627869 |
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