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Decreased Ferroportin Promotes Myeloma Cell Growth and Osteoclast Differentiation

Iron homeostasis is disrupted in multiple myeloma, a difficult-to-cure plasma cell malignancy with lytic bone lesions. Here, we systematically analyzed iron gene expression signature and demonstrated that mRNA expression of iron exporter ferroportin (FPN1) is significantly downregulated in myeloma c...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Gu, Zhimin, Wang, He, Xia, Jiliang, Yang, Ye, Jin, Zhendong, Xu, Hongwei, Shi, Jumei, De Domenico, Ivana, Tricot, Guido, Zhan, Fenghuang
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946247/
https://ncbi.nlm.nih.gov/pubmed/25855377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3804
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