Multiple Myeloma Tumor Cells are Selectively Killed by Pharmacologically-dosed Ascorbic Acid

High-dose chemotherapies to treat multiple myeloma (MM) can be life-threatening due to toxicities to normal cells and there is a need to target only tumor cells and/or lower standard drug dosage without losing efficacy. We show that pharmacologically-dosed ascorbic acid (PAA), in the presence of iro...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Xia, Jiliang, Xu, Hongwei, Zhang, Xiaoyan, Allamargot, Chantal, Coleman, Kristen L., Nessler, Randy, Frech, Ivana, Tricot, Guido, Zhan, Fenghuang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405162/
https://ncbi.nlm.nih.gov/pubmed/28229908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.02.011
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