Decreased Ferroportin Promotes Myeloma Cell Growth and Osteoclast Differentiation

Iron homeostasis is disrupted in multiple myeloma, a difficult-to-cure plasma cell malignancy with lytic bone lesions. Here, we systematically analyzed iron gene expression signature and demonstrated that mRNA expression of iron exporter ferroportin (FPN1) is significantly downregulated in myeloma c...

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Foilsithe in:Cancer Res
Main Authors: Gu, Zhimin, Wang, He, Xia, Jiliang, Yang, Ye, Jin, Zhendong, Xu, Hongwei, Shi, Jumei, De Domenico, Ivana, Tricot, Guido, Zhan, Fenghuang
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946247/
https://ncbi.nlm.nih.gov/pubmed/25855377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3804
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