P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age

Senescent cells are more prevalent in aged human skin compared to young, but evidence that senescent cells are linked to other biomarkers of aging is scarce. We counted cells positive for the tumor suppressor and senescence associated protein p16INK4a in sun-protected upper-inner arm skin biopsies f...

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Bibliografische gegevens
Gepubliceerd in:J Gerontol A Biol Sci Med Sci
Hoofdauteurs: Waaijer, Mariëtte E. C., Gunn, David A., Adams, Peter D., Pawlikowski, Jeff S., Griffiths, Christopher E. M., van Heemst, Diana, Slagboom, P. Eline, Westendorp, Rudi G. J., Maier, Andrea B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945882/
https://ncbi.nlm.nih.gov/pubmed/26286607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv114
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