The number of p16INK4a positive cells in human skin reflects biological age

Cellular senescence is a defense mechanism in response to molecular damage which accumulates with aging. Correspondingly, the number of senescent cells has been reported to be greater in older than in younger subjects and furthermore associates with age-related pathologies. Inter-individual differen...

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Detalhes bibliográficos
Main Authors: Waaijer, Mariëtte E.C., Parish, William E., Strongitharm, Barbara H., van Heemst, Diana, Slagboom, Pieternella E., de Craen, Anton J.M., Sedivy, John M., Westendorp, Rudi G.J., Gunn, David A., Maier, Andrea B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539756/
https://ncbi.nlm.nih.gov/pubmed/22612594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00837.x
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