P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age

Senescent cells are more prevalent in aged human skin compared to young, but evidence that senescent cells are linked to other biomarkers of aging is scarce. We counted cells positive for the tumor suppressor and senescence associated protein p16INK4a in sun-protected upper-inner arm skin biopsies f...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Waaijer, Mariëtte E. C., Gunn, David A., Adams, Peter D., Pawlikowski, Jeff S., Griffiths, Christopher E. M., van Heemst, Diana, Slagboom, P. Eline, Westendorp, Rudi G. J., Maier, Andrea B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945882/
https://ncbi.nlm.nih.gov/pubmed/26286607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv114
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