P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age

Senescent cells are more prevalent in aged human skin compared to young, but evidence that senescent cells are linked to other biomarkers of aging is scarce. We counted cells positive for the tumor suppressor and senescence associated protein p16INK4a in sun-protected upper-inner arm skin biopsies f...

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Bibliografiske detaljer
Udgivet i:J Gerontol A Biol Sci Med Sci
Main Authors: Waaijer, Mariëtte E. C., Gunn, David A., Adams, Peter D., Pawlikowski, Jeff S., Griffiths, Christopher E. M., van Heemst, Diana, Slagboom, P. Eline, Westendorp, Rudi G. J., Maier, Andrea B.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945882/
https://ncbi.nlm.nih.gov/pubmed/26286607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv114
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