Skeletal muscle–specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21–mediated non–cell-autonomous energy metabolism

The eukaryotic translation initiation factor 2α (eIF2α) phosphorylation-dependent integrated stress response (ISR), a component of the unfolded protein response, has long been known to regulate intermediary metabolism, but the details are poorly worked out. We report that profiling of mRNAs of trans...

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Veröffentlicht in:FASEB J
Hauptverfasser: Miyake, Masato, Nomura, Akitoshi, Ogura, Atsushi, Takehana, Kenji, Kitahara, Yoshihiro, Takahara, Kazuna, Tsugawa, Kazue, Miyamoto, Chinobu, Miura, Naoko, Sato, Ryosuke, Kurahashi, Kiyoe, Harding, Heather P., Oyadomari, Miho, Ron, David, Oyadomari, Seiichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2016
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945323/
https://ncbi.nlm.nih.gov/pubmed/26487695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275990
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