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The Molecular Switching Mechanism at the Conserved D(E)RY Motif in Class-A GPCRs
The disruption of ionic and H-bond interactions between the cytosolic ends of transmembrane helices TM3 and TM6 of class-A (rhodopsin-like) G protein-coupled receptors (GPCRs) is a hallmark for their activation by chemical or physical stimuli. In the bovine photoreceptor rhodopsin, this is accompani...
Shranjeno v:
| izdano v: | Biophys J |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945304/ https://ncbi.nlm.nih.gov/pubmed/27410736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.06.004 |
| Oznake: |
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