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The Molecular Switching Mechanism at the Conserved D(E)RY Motif in Class-A GPCRs
The disruption of ionic and H-bond interactions between the cytosolic ends of transmembrane helices TM3 and TM6 of class-A (rhodopsin-like) G protein-coupled receptors (GPCRs) is a hallmark for their activation by chemical or physical stimuli. In the bovine photoreceptor rhodopsin, this is accompani...
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| Publicat a: | Biophys J |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945304/ https://ncbi.nlm.nih.gov/pubmed/27410736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.06.004 |
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