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Exploiting DNA repair defects for novel cancer therapies
Most human tumors accumulate a multitude of genetic changes due to defects in the DNA damage response. Recently, small-molecule inhibitors have been developed that target cells with specific DNA repair defects, providing hope for precision treatment of such tumors. Here we discuss the rationale behi...
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| 出版年: | Mol Biol Cell |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Cell Biology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945134/ https://ncbi.nlm.nih.gov/pubmed/27418635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-10-0698 |
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